It is very important you backup your MSDE database.  It is important to understand, the database file is in-use by the database server at all times.  This means a file based backup utility will not  backup the database correctly.  You must use a tool specifically made to backup SQL Server/MSDE database. 

In addition to backing up your database, it is always good practice to periodically restore the database to make sure your backups are successful.  You should not restore to your Timeless MSDE server, but to a different MSDE server.

There are 4 choices for backing up your Timeless MSDE database.  In all cases, an administrator on the server machine can use Integrated security to backup the database.

Microsoft SQL Server Enterprise Manager
If you have SQL Server, you can use Enterprise Manager.  You already have it and are most likely backing up other database, so use it.  Talk to your database administrator and have them assist you.

Microsoft SQL Server Management Studio Express
This is a free download for managing SQL Server 2005 Express, but it will also manage MSDE databases.  If you are receiving insufficient access rights errors when backing up using SQL Server Management Studio Express, this article may help.

Third-party MSDE management tools
These tools are much like Enterprise Manager, but for companies without SQL Server, they are often less expensive.  There are many to choose from.  Because they use the MSDE Server, they have similar functionality.  Pick the one that works best for you. 

Microsoft Access 2000 or later
If you have Access 2000 or later, you can use it to backup your database.  However, the backup cannot be scheduled.  We highly recommend the backup be scheduled.  All too often, manual backup do not take place because there are always more pressing priorities.  But if a backup is needed and you want to be sure it is current.  See the Microsoft Access help for details.

OSQL
Osql is a command line utility for issuing commands to SQL Server\MSDE.  This is by far the least expensive and most flexible solution.  However, it is much more complex and error prone than the other options.  You can find Osql at \Program Files\Microsoft SQL Server\80\Tools\Binn on the machine the Timeless MSDE server was installed on.  Here is an article to assist you in using Osql.